Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 14/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23538213 | 0.87 | DEGS1 (0.40) | FFAR4LIPGDGAT1LPL | |
| SCHEMBL23551417 | 0.85 | MAPT (0.42) | LIPGITGB3ITGA2BDGAT1LPL | |
| SCHEMBL2053569 | 0.84 | LIPG (0.41) | LIPGLPLUSP2 | |
| SCHEMBL24847168 | 0.82 | LPL (0.39) | FFAR1LIPGLPL | |
| SCHEMBL31341877 | 0.81 | LPL (0.40) | LIPGLPL | |
| SCHEMBL14862313 | 0.80 | LPL (0.42) | LIPGLPLUSP2P4HB | |
| SCHEMBL2255428 | 0.80 | HIF1A (0.46) | LIPGDGAT1 | |
| SCHEMBL22636528 | 0.80 | S1PR1 (0.50) | LIPGITGB3ITGA2BLPLUSP2 | |
| SCHEMBL2255432 | 0.80 | HIF1A (0.46) | LIPGDGAT1 | |
| SCHEMBL24681610 | 0.78 | LPL (0.46) | LIPGLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417127-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | University Health Network (CA) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115279-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2010-10-14 | — | — | WO | disclosed |