Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 11/20 | 0.54 |
| ▸ | CDK1 | P06493 | 11/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 11/20 | 0.54 |
| ▸ | CCNB3 | Q8WWL7 | 11/20 | 0.54 |
| ▸ | CDK2 | P24941 | 7/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148905 | 0.86 | CDK2 (0.54) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL6016594 | 0.78 | CDK2 (0.59) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL6016512 | 0.78 | CDK1 (0.78) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL6016451 | 0.77 | CDK2 (0.63) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL6016456 | 0.77 | CDK2 (0.63) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL26936162 | 0.76 | CDK1 (0.59) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL6016566 | 0.74 | LMNA (0.42) | — | |
| SCHEMBL756298 | 0.72 | YTHDC1 (0.62) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL6016636 | 0.71 | CDK1 (0.62) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL6016516 | 0.71 | EGFR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244668-B1 | PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | UNIVERSITAIRE INSTELLING ANTWE (BE) | 2006-04-05 | — | — | EP | claimed |
| US-20030187261-A1 | Purine derivatives, process for their preparation and use thereof | USTAV EXPERIMANTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY (CZ) | 2003-10-02 | — | — | US | claimed |
| EP-1244668-A1 | PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 2002-10-02 | — | — | EP | claimed |
| WO-2001049688-A1 | PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 2001-07-12 | — | — | WO | claimed |
| US-20030187261-A1 | Purine derivatives, process for their preparation and use thereof | USTAV EXPERIMANTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY (CZ) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187261-A1 | Purine derivatives, process for their preparation and use thereof | DCK, DTYMK, CCNK | CCNB2 127/4885CDK1 7/4885CCNB1 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.