Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.63 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016597 | 0.92 | TACR1 (0.52) | TACR1SGMS2 | |
| SCHEMBL6016561 | 0.92 | TACR1 (0.52) | TACR1SGMS2BRAF | |
| SCHEMBL6016649 | 0.91 | TACR1 (0.77) | TACR1BRAF | |
| SCHEMBL6016699 | 0.91 | TACR1 (0.65) | TACR1BRAF | |
| SCHEMBL6016733 | 0.91 | TACR1 (0.65) | TACR1 | |
| SCHEMBL6016428 | 0.90 | TACR1 (0.64) | TACR1SGMS2 | |
| SCHEMBL6016586 | 0.90 | TACR1 (0.64) | TACR1 | |
| SCHEMBL7042999 | 0.89 | TACR1 (0.62) | TACR1SGMS2 | |
| SCHEMBL6016533 | 0.87 | TACR1 (0.48) | TACR1 | |
| SCHEMBL6016547 | 0.85 | TACR1 (0.57) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187815-B1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-02-08 | — | — | EP | claimed |