Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.57 |
| ▸ | CENPE | Q02224 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CASP1 | P29466 | 5/20 | 0.41 |
| ▸ | CASP7 | P55210 | 5/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016619 | 0.91 | TACR1 (0.47) | TACR1CENPEUSP2ALDH1A1CASP1 | |
| SCHEMBL6016733 | 0.88 | TACR1 (0.65) | TACR1 | |
| SCHEMBL6016699 | 0.88 | TACR1 (0.65) | TACR1 | |
| SCHEMBL6016649 | 0.86 | TACR1 (0.77) | TACR1 | |
| SCHEMBL6016428 | 0.85 | TACR1 (0.64) | TACR1 | |
| SCHEMBL6016586 | 0.85 | TACR1 (0.64) | TACR1 | |
| SCHEMBL6016646 | 0.85 | TACR1 (0.63) | TACR1 | |
| SCHEMBL6016548 | 0.81 | TACR1 (0.54) | TACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6016610 | 0.81 | TACR1 (0.54) | TACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6862187 | 0.80 | TACR1 (0.62) | TACR1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187815-B1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-02-08 | — | — | EP | claimed |