Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 11/20 | 0.69 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.69 |
| ▸ | CCNE2 | O96020 | 9/20 | 0.69 |
| ▸ | CDK1 | P06493 | 9/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.65 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.65 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.65 |
| ▸ | PDE5A | O76074 | 1/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.65 |
| ▸ | CDK7 | P50613 | 1/20 | 0.65 |
| ▸ | CDK9 | P50750 | 1/20 | 0.65 |
| ▸ | CCNH | P51946 | 1/20 | 0.65 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.65 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.65 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.61 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3332989 | 0.91 | CDK1 (0.76) | CDK2CCNE1CCNE2CDK1CCNB1 | |
| SCHEMBL14071580 | 0.82 | CDK2 (0.85) | CDK2CCNE1CCNE2CDK1CCNB1 | |
| SCHEMBL2364042 | 0.80 | CDK1 (0.87) | CDK2CCNE1CCNE2CDK1CCNB1 | |
| SCHEMBL3680752 | 0.80 | CCNE1 (0.82) | CDK2CCNE1CCNE2CDK1CCNB1 | |
| SCHEMBL6143053 | 0.80 | CDK2 (1.00) | CDK2CCNE1CCNE2CDK1CCNB1 | |
| SCHEMBL1394958 | 0.79 | CCNE2 (1.00) | CDK2CCNE1CCNE2CDK1CCNB1 | |
| SCHEMBL5827556 | 0.78 | CCNE2 (0.78) | CDK2CCNE1CCNE2CDK1CCNB1 | |
| SCHEMBL4277404 | 0.78 | CDK1 (1.00) | CDK2CCNE1CCNE2CDK1CCNB1 | |
| SCHEMBL5828748 | 0.77 | CCNE1 (0.75) | CDK2CCNE1CCNE2CDK1CCNB1 | |
| SCHEMBL6016706 | 0.76 | CDK1 (1.00) | CDK2CCNE1CCNE2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244668-B1 | PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | UNIVERSITAIRE INSTELLING ANTWE (BE) | 2006-04-05 | — | — | EP | disclosed |