Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 3/20 | 0.36 |
| ▸ | NR5A2 | O00482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | PPP5C | P53041 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1089052 | 0.64 | SLC1A2 (0.38) | MEN1KMT2A | |
| SCHEMBL8679556 | 0.63 | NR5A1 (0.42) | NR5A1NR5A2MEN1KMT2A | |
| SCHEMBL8679558 | 0.63 | NR5A1 (0.42) | NR5A1NR5A2MEN1KMT2A | |
| SCHEMBL27216297 | 0.63 | CYP3A4 (0.37) | MEN1KMT2AHCAR2DPP4 | |
| SCHEMBL12329169 | 0.61 | ARG1 (0.43) | MEN1KMT2APPP5C | |
| SCHEMBL9657672 | 0.61 | GRM2 (0.33) | — | |
| SCHEMBL28434026 | 0.61 | MEN1 (0.45) | MEN1KMT2AHCAR2 | |
| SCHEMBL29265385 | 0.59 | SMN1; SMN2 (0.38) | — | |
| Pentane SCHEMBL28925919 | 0.59 | EPHX2 (0.33) | MEN1KMT2A | |
| SCHEMBL25473438 | 0.59 | ALDH1A1 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615886-A1 | [C]-FUSED BICYCLIC PROLINE DERIVATIVES AND THEIR USE FOR TREATING ARTHRITIC CONDITIONS | Warner-Lambert Company LLC (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004092134-A1 | [C]-FUSED BICYCLIC PROLINE DERIVATIVES AND THEIR USE FOR TREATING ARTHRITIC CONDITIONS | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-28 | — | — | WO | disclosed |