Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CCL2 | P13500 | 1/20 | 0.30 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016952 | 0.84 | F10 (0.46) | F10F2ALDH1A1L3MBTL1IDO1 | |
| SCHEMBL6016870 | 0.80 | F10 (0.39) | F10F2ALDH1A1IDO1POLB | |
| SCHEMBL6017047 | 0.80 | F10 (0.39) | F10F2ALDH1A1IDO1POLB | |
| SCHEMBL6016990 | 0.79 | F10 (0.36) | F10F2ALDH1A1POLBGAA | |
| SCHEMBL3369950 | 0.78 | F10 (0.43) | F10F2ALDH1A1L3MBTL1POLB | |
| SCHEMBL6016887 | 0.77 | F10 (0.50) | F10F2ALDH1A1L3MBTL1 | |
| SCHEMBL6017043 | 0.75 | F10 (0.35) | F10F2ALDH1A1POLB | |
| SCHEMBL1382572 | 0.71 | F10 (0.61) | F10F2 | |
| SCHEMBL6257006 | 0.69 | F10 (0.44) | F10F2ALDH1A1L3MBTL1POLB | |
| SCHEMBL6016954 | 0.66 | F10 (0.55) | F10F2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |