Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016952 | 0.80 | F10 (0.46) | F10F2ALDH1A1IDO1POLB | |
| SCHEMBL6016885 | 0.80 | F10 (0.38) | F10F2ALDH1A1BRD4CCL2 | |
| SCHEMBL6016870 | 0.78 | F10 (0.39) | F10F2ALDH1A1IDO1POLB | |
| SCHEMBL6017050 | 0.77 | F10 (0.49) | F10F2ALDH1A1CCNKCDK12 | |
| SCHEMBL6016990 | 0.76 | F10 (0.36) | F10F2ALDH1A1POLBNPSR1 | |
| SCHEMBL3369990 | 0.75 | ACSS2 (0.45) | F10F2ALDH1A1CCNKCDK12 | |
| SCHEMBL6017043 | 0.74 | F10 (0.35) | F10F2ALDH1A1POLBNPSR1 | |
| SCHEMBL3373231 | 0.73 | F10 (0.42) | F10F2ALDH1A1CCNKCDK12 | |
| SCHEMBL3369492 | 0.72 | ALDH1A1 (0.43) | F10F2ALDH1A1IDO1POLB | |
| SCHEMBL6257006 | 0.69 | F10 (0.44) | F10F2ALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |