Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | MOK | Q9UQ07 | 2/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016990 | 0.87 | F10 (0.36) | F10F2WNT1GSK3BDYRK1A | |
| SCHEMBL6017044 | 0.77 | F10 (0.45) | F10F2WNT1GSK3BDYRK1A | |
| SCHEMBL3370026 | 0.75 | ALDH1A1 (0.39) | F10F2MOKALDH1A1MEN1 | |
| SCHEMBL6016885 | 0.75 | F10 (0.38) | F10F2ALDH1A1POLB | |
| SCHEMBL6017047 | 0.74 | F10 (0.39) | F10F2ALDH1A1NPSR1POLB | |
| SCHEMBL6016952 | 0.73 | F10 (0.46) | F10F2ALDH1A1NPSR1POLB | |
| SCHEMBL3371009 | 0.71 | MOK (0.44) | F10F2MOKALDH1A1MEN1 | |
| SCHEMBL1383480 | 0.71 | F10 (0.55) | F10F2 | |
| SCHEMBL6016992 | 0.71 | F10 (0.46) | F10F2MOKKMT2A | |
| SCHEMBL6016870 | 0.71 | F10 (0.39) | F10F2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |