Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.45 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.39 |
| ▸ | KMT5A | Q9NQR1 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033412 | 0.90 | EHMT2 (0.38) | EHMT2EHMT1HRH4SLC2A1SPIN1 | |
| SCHEMBL6237774 | 0.89 | EHMT2 (0.45) | EHMT2EHMT1HRH4SLC2A1SPIN1 | |
| SCHEMBL4874024 | 0.86 | HRH4 (0.57) | HRH4 | |
| SCHEMBL6609401 | 0.86 | EHMT2 (0.41) | EHMT2EHMT1HRH4SLC2A1SPIN1 | |
| SCHEMBL6016881 | 0.85 | MAPK1 (0.36) | EHMT2EHMT1HRH4SLC2A1SPIN1 | |
| SCHEMBL5556168 | 0.83 | SMN1; SMN2 (0.41) | HRH4SMN1; SMN2MAPK1RECQLBCL6 | |
| SCHEMBL5037951 | 0.80 | EHMT2 (0.47) | EHMT2EHMT1HRH4PGR | |
| SCHEMBL6430010 | 0.80 | EHMT2 (0.37) | EHMT2EHMT1SPIN1NMT1 | |
| SCHEMBL4836469 | 0.80 | HRH4 (0.45) | HRH4SMN1; SMN2MAPK1 | |
| SCHEMBL5421592 | 0.79 | EHMT2 (0.39) | EHMT2EHMT1HRH4SLC2A1SPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | disclosed |