Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369253 | 0.90 | GRM5 (0.43) | F10KMT2AMOKGRM5MAPK1 | |
| SCHEMBL1381845 | 0.90 | F10 (0.56) | F10F2HRH3KMT2A | |
| SCHEMBL6017044 | 0.85 | F10 (0.45) | F10F2KMT2AMOK | |
| SCHEMBL3368811 | 0.84 | F10 (0.51) | F10F2HRH3KMT2AMOK | |
| SCHEMBL6017050 | 0.83 | F10 (0.49) | F10F2PADI4CCNT1CDK9 | |
| SCHEMBL1652749 | 0.81 | F10 (0.69) | F10F2 | |
| SCHEMBL3231945 | 0.79 | F10 (0.55) | F10F2HRH3 | |
| SCHEMBL3369596 | 0.78 | F10 (0.65) | F10F2 | |
| SCHEMBL3236594 | 0.78 | GRM5 (0.44) | F10F2HRH3KMT2AMOK | |
| SCHEMBL1379542 | 0.78 | F10 (0.60) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |