Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CASP14 | P31944 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829503 | 0.94 | MAP3K8 (0.42) | RAB9AMAP3K8SYKTSHRSIGMAR1 | |
| SCHEMBL5471457 | 0.93 | MAP3K8 (0.41) | RAB9AMAP3K8SYKTSHRSIGMAR1 | |
| Hydrochloric Acid SCHEMBL5555480 | 0.93 | MAP3K8 (0.41) | RAB9AMAP3K8SYKTSHRSIGMAR1 | |
| Hydrochloric Acid SCHEMBL4832271 | 0.92 | MAP3K8 (0.41) | RAB9AMAP3K8SYKTSHRSIGMAR1 | |
| SCHEMBL4832147 | 0.92 | SIGMAR1 (0.47) | RAB9AMAP3K8TSHRSIGMAR1CTSS | |
| Hydrochloric Acid SCHEMBL5438482 | 0.92 | MAP3K8 (0.40) | RAB9AMAP3K8SYKTSHRSIGMAR1 | |
| SCHEMBL14454082 | 0.91 | RAB9A (0.39) | RAB9AMAP3K8SYKTSHRSIGMAR1 | |
| SCHEMBL14421592 | 0.89 | RAB9A (0.44) | RAB9AMAP3K8TSHRSIGMAR1CTSS | |
| SCHEMBL4829223 | 0.88 | BCL6 (0.51) | RAB9AMAP3K8CTSSCTSKCTSL | |
| SCHEMBL4837026 | 0.87 | BCL6 (0.44) | RAB9AMAP3K8KDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112587-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2006-09-26 | — | — | US | disclosed |