Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690303 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| SCHEMBL9988562 | 0.81 | TSHR (0.46) | ALDH1A1TSHRMAPK1RARBTP53 | |
| SCHEMBL9452464 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| SCHEMBL20520150 | 0.80 | RARB (0.43) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| SCHEMBL9988564 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| SCHEMBL10299488 | 0.78 | HCAR3 (0.54) | ALDH1A1HCAR3TSHRMAPK1RARB | |
| SCHEMBL45364 | 0.78 | ALDH1A1 (0.49) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| Aminobenzoic Acid SCHEMBL8537849 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| SCHEMBL25432801 | 0.77 | TSHR (0.54) | ALDH1A1CYP3A4LMNAHSD17B10TSHR | |
| SCHEMBL2131653 | 0.77 | ALDH1A1 (0.67) | ALDH1A1CYP3A4LMNAHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692160-A2 | FGF-5 BINDING AND SUPPORTED PEPTIDES | GENENCOR INTERNATIONAL, INC. (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005047314-A2 | FGF-BETA BINDING AND SUPPORTED PEPTIDES | GENENCOR INTERNATIONAL, INC. (US) | 2005-05-26 | — | — | WO | disclosed |