Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.47 |
| ▸ | PPARA | Q07869 | 12/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017244 | 0.93 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL6017227 | 0.91 | PKM (0.41) | PPARDPPARAPPARG | |
| SCHEMBL5617387 | 0.87 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL5617384 | 0.83 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL5617389 | 0.82 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL6017193 | 0.81 | PPARD (0.40) | PPARDPPARAPPARG | |
| SCHEMBL6052637 | 0.81 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL5859790 | 0.81 | PPARD (0.72) | PPARDPPARAPPARG | |
| SCHEMBL6064615 | 0.80 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL6017170 | 0.79 | PPARD (0.38) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682535-A1 | HETEROARYL DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005049606-A1 | HETEROARYL DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-02 | — | — | WO | disclosed |