Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2971945 | 0.71 | KDM4E (0.35) | TSHR | |
| SCHEMBL207490 | 0.71 | AHR (0.42) | TSHR | |
| SCHEMBL207776 | 0.71 | AHR (0.42) | TSHR | |
| SCHEMBL1399575 | 0.71 | NOS1 (0.35) | — | |
| SCHEMBL1923230 | 0.71 | HTR1D (0.39) | — | |
| SCHEMBL28463442 | 0.71 | KIF11 (0.41) | TSHR | |
| SCHEMBL28464304 | 0.66 | KIF11 (0.37) | — | |
| SCHEMBL28458649 | 0.66 | KIF11 (0.37) | — | |
| SCHEMBL28463432 | 0.66 | KIF11 (0.37) | — | |
| SCHEMBL4493688 | 0.65 | KDM4E (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508143-A | Optical recording medium | PIONEER ELECTRONIC CORPORATION (JP) | 1996-04-16 | — | — | US | claimed |
| EP-1682535-A1 | HETEROARYL DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005049606-A1 | HETEROARYL DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-02 | — | — | WO | disclosed |
| US-5508143-A | Optical recording medium | PIONEER ELECTRONIC CORPORATION (JP) | 1996-04-16 | — | — | US | disclosed |