Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523173 | 0.91 | TACR1 (0.47) | TACR1CNR1KMT2ARAB9AALDH1A1 | |
| SCHEMBL78208 | 0.91 | TACR1 (0.47) | TACR1CNR1KMT2ARAB9AALDH1A1 | |
| SCHEMBL21679925 | 0.91 | TACR1 (0.47) | TACR1CNR1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4558186 | 0.80 | TACR1 (0.39) | TACR1CNR1RAB9A | |
| SCHEMBL6017344 | 0.79 | TACR1 (0.47) | TACR1CNR1KMT2ALMNAALDH1A1 | |
| SCHEMBL11484911 | 0.78 | TACR1 (0.44) | TACR1CNR1RAB9AALDH1A1 | |
| SCHEMBL5605674 | 0.78 | TACR1 (0.46) | TACR1CNR1KMT2ARAB9ALMNA | |
| SCHEMBL7511083 | 0.77 | CNR1 (0.47) | TACR1CNR1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11091144 | 0.77 | CNR1 (0.49) | TACR1CNR1ALDH1A1 | |
| SCHEMBL11485859 | 0.76 | TACR1 (0.47) | TACR1CNR1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680458-A2 | ROMP WITH FLUORINATED GROUPS | Ciba SC Holding AG (CH) | 2006-07-19 | — | — | EP | disclosed |
| EP-1539873-A2 | STABILLIZATION OF ORGANIC MATERIALS | Ciba SC Holding AG (CH) | 2005-06-15 | — | — | EP | disclosed |
| WO-2005028402-A2 | ROMP WITH FLUORINATED GROUPS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-03-31 | — | — | WO | disclosed |
| WO-2004024810-A2 | STABILLIZATION OF ORGANIC MATERIALS | CIBA, SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-03-25 | — | — | WO | disclosed |