Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | PGR | P06401 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924871 | 1.00 | SHBG (0.71) | SHBGALDH1A1CYP19A1HIF1ALMNA | |
| SCHEMBL11691797 | 1.00 | SHBG (0.71) | SHBGALDH1A1CYP19A1HIF1ALMNA | |
| SCHEMBL11691787 | 1.00 | SHBG (0.71) | SHBGALDH1A1CYP19A1HIF1ALMNA | |
| SCHEMBL14318934 | 0.84 | NR3C1 (0.58) | SHBGALDH1A1CYP19A1HIF1ALMNA | |
| Calusterone SCHEMBL4509 | 0.83 | SHBG (1.00) | SHBGALDH1A1CYP19A1HIF1ALMNA | |
| Bolasterone SCHEMBL11876760 | 0.83 | SHBG (1.00) | SHBGALDH1A1CYP19A1HIF1ALMNA | |
| Bolasterone SCHEMBL4945157 | 0.83 | SHBG (1.00) | SHBGALDH1A1CYP19A1HIF1ALMNA | |
| Bolasterone SCHEMBL145066 | 0.83 | SHBG (1.00) | SHBGALDH1A1CYP19A1HIF1ALMNA | |
| Bolasterone SCHEMBL10904938 | 0.83 | SHBG (1.00) | SHBGALDH1A1CYP19A1HIF1ALMNA | |
| Bolasterone SCHEMBL5656551 | 0.83 | SHBG (1.00) | SHBGALDH1A1CYP19A1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018648-B2 | Transdermal device for administering testosterone or one of the derivatives thereof | PIERRE FABRE MEDICAMENT (FR) | 2006-03-28 | — | — | US | disclosed |
| US-20050256051-A1 | Nuclear receptor-mediated introduction of a PNA into cell nuclei | THE POPULATION COUNCIL, INC. (US) | 2005-11-17 | — | — | US | disclosed |
| US-20050100586-A1 | Transdermal device for administering testosterone or one of the derivatives thereof | PIERRE FABRE MEDICAMENT (FR) | 2005-05-12 | — | — | US | disclosed |
| EP-1178806-B1 | TRANSDERMAL DEVICE FOR THE APPLICATION OF TESTOSTERONE OR ONE OF THE DERIVATIVES THEREOF | PF MEDICAMENT (FR) | 2004-09-01 | — | — | EP | disclosed |
| US-6767902-B2 | Androgen as a male contraceptive and non-contraceptive androgen replacement | THE POPULATION COUNCIL, INC. | 2004-07-27 | — | — | US | disclosed |
| US-20040132698-A1 | Androgen as a male contraceptive and non-contraceptive androgen replacement | MOO-YOUNG ALFRED J (US) | 2004-07-08 | — | — | US | disclosed |
| US-20040126418-A1 | Transdermal administration of MENT | THE POPULATION COUNCIL, INC. | 2004-07-01 | — | — | US | disclosed |
| US-20030096739-A1 | Nuclear receptor-mediated introduction of a PNA into cell nuclei | POPULATION COUNCIL, INC., THE | 2003-05-22 | — | — | US | disclosed |
| US-20020193359-A1 | Administering to a non-sterile male subject a predetermined amount of an androgen which is sufficient to render male subject reversibly sterile for a predetermined period of time | POPULATION COUNCIL, INC., THE | 2002-12-19 | — | — | US | disclosed |
| US-20020012694-A1 | TRANSDERMAL ADMINISTRATION OF MENT | POPULATION COUNCIL, INC., THE, A CORP. OF NY | 2002-01-31 | — | — | US | disclosed |
| US-5342834-A | Administering testosterone derivatives | THE POPULATION COUNCIL, INC. (US) | 1994-08-30 | — | — | US | disclosed |