Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KDM1A | O60341 | 3/20 | 0.62 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608221 | 0.88 | ROCK1 (0.57) | MCL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9410553 | 0.85 | THRB (0.63) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL14626728 | 0.84 | PTGDR2 (0.59) | MCL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9410563 | 0.82 | SMN1; SMN2 (0.67) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL1093913 | 0.82 | MCL1 (0.67) | MCL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL29581946 | 0.82 | MCL1 (0.67) | MCL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL13406296 | 0.82 | KDM4E (0.56) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL6989729 | 0.81 | ROCK1 (0.53) | MCL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14591857 | 0.81 | PTGDR2 (0.56) | MCL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30525414 | 0.81 | MCL1 (0.65) | MCL1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790161-A | Pyrazolopyridine derivatives having GLP-1 receptor agonist action | 中外制药株式会社 | 2019-05-21 | — | — | CN | disclosed |
| US-7071199-B1 | Kinase inhibitors as therapeutic agents | ABBOTT GMBH & CCO. KG (DE) | 2006-07-04 | — | — | US | disclosed |