SCHEMBL6017879

SCHEMBL6017879

Nc1ccc(C(=O)Nc2ccc3cc(S(=O)(=O)O)cc(O)c3c2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 4/20 0.84
CTDSP1 Q9GZU7 1/20 0.84
NT5E P21589 2/20 0.69
ENPP2 Q13822 3/20 0.60
PRMT1 Q99873 4/20 0.55
NSD2 O96028 3/20 0.55
DUSP3 P51452 2/20 0.55
PTPN5 P54829 2/20 0.55
PTPN11 Q06124 2/20 0.55
CASP7 P55210 1/20 0.55
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA12 O43570 1/20 0.54
CA9 Q16790 1/20 0.54
APEX1 P27695 2/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
POLB P06746 1/20 0.50
PKM P14618 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2184239 0.91 CASP6 (1.00) CASP6CTDSP1NT5EENPP2PRMT1
SCHEMBL29495050 0.91 CASP6 (1.00) CASP6CTDSP1NT5EENPP2PRMT1
SCHEMBL11434098 0.90 CASP6 (0.72) CASP6CTDSP1NT5EENPP2PRMT1
SCHEMBL30646175 0.90 CASP6 (0.98) CASP6CTDSP1NT5EENPP2PRMT1
SCHEMBL14413308 0.90 CASP6 (0.98) CASP6CTDSP1NT5EENPP2PRMT1
SCHEMBL26885948 0.90 NT5E (0.68) CASP6CTDSP1NT5EENPP2PRMT1
SCHEMBL10905567 0.89 CASP6 (0.67) CASP6CTDSP1NT5EENPP2PRMT1
SCHEMBL11211030 0.89 PRMT1 (0.67) CASP6CTDSP1NT5EENPP2PRMT1
SCHEMBL10326996 0.89 ENPP2 (0.71) CASP6CTDSP1NT5EENPP2PRMT1
SCHEMBL7897823 0.88 CASP6 (0.65) CASP6CTDSP1NT5EENPP2PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112534316-A Polarizing element, and polarizing plate and optical member using the same 日本化药株式会社 2021-03-19 CN disclosed
US-10150871-B2 Azo compound, dye-based polarizing film containing same, and polarizing plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-12-11 US disclosed
CN-106164181-B Azo compound, and dye-type polarizing film and polarizing plate containing the same 日本化药株式会社 2018-11-02 CN disclosed
US-20170210902-A1 Azo Compound, Dye-Based Polarizing Film Containing Same, And Polarizing Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-07-27 US disclosed
EP-3127965-A1 AZO COMPOUND, DYE-BASED POLARIZING FILM CONTAINING SAME, AND POLARIZING PLATE Nippon Kayaku Kabushiki Kaisha (JP) 2017-02-08 EP disclosed
CN-106164181-A Azo compound, and dye-type polarizing film and polarizing plate containing the same 日本化药株式会社 2016-11-23 CN disclosed
US-7066969-B2 Dyes incorporating annionic and cationic groups CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-06-27 US disclosed
US-20040205912-A1 Dyes incorporating annionic and cationic groups CIBA SPECIALTY CHEMICALS CORP. 2004-10-21 US disclosed
EP-1055710-B1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2004-08-11 EP disclosed
EP-1442082-A1 DYES INCORPORATING ANIONIC AND CATIONIC GROUPS Ciba SC Holding AG (CH) 2004-08-04 EP disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0542079-A2 Process for continuously reacting halogenopyrimidines with amines BAYER AG (DE) 1993-05-19 EP disclosed
EP-0542214-A2 Water-soluble fibre-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed
US-5091515-A PROCESS FOR THE PREPARATION OF SUBSTITUTED 2,4-DIAMINO-6-FLUORO-S-TRIAZINES BAYER AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
EP-0013784-B1 C-SUBSTITUTED NAPHTHALENEMONOSULFONIC UREIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AMERICAN CYANAMID COMPANY (US) 1983-02-23 EP disclosed
US-4297372-A ANTIARTHRITIC AGENTS; COLLAGENASE AND PROTEOLYTIC ENZYME INHIBITORS; BONE, SKIN, AND ORAL DISORDERS AMERICAN CYANAMID COMPANY (US) 1981-10-27 US disclosed
EP-0013784-A1 C-Substituted naphthalenemonosulfonic ureides, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1980-08-06 EP disclosed
US-4216165-A Amine precursors to ureide inhibitors of connective tissue destruction AMERICAN CYANAMID COMPANY (US) 1980-08-05 US disclosed
US-4216164-A Ureide inhibitors of connective tissue destruction AMERICAN CYANAMID COMPANY (US) 1980-08-05 US disclosed
US-4216166-A Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction AMERICAN CYANAMID COMPANY (US) 1980-08-05 US disclosed