SCHEMBL6018229

SCHEMBL6018229

C=CC1=NC(=O)C(C)(C)O1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5186829 0.71 MEN1 (0.30) GAA
SCHEMBL10972855 0.71
SCHEMBL15866343 0.67
SCHEMBL11929669 0.64 ALDH1A1 (0.39) ALDH1A1GAAMAPK1
SCHEMBL12341161 0.64
SCHEMBL12975632 0.62 ALDH1A1 (0.32) ALDH1A1GAAMAPK1
SCHEMBL17375481 0.60
SCHEMBL260328 0.60
SCHEMBL20369097 0.60 PTGS2 (0.33) ALDH1A1GAAMAPK1
SCHEMBL541381 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115379826-B Boundary surface charged contact lens for delivery 领视药公司 2023-07-21 CN claimed
CN-113226247-A Resin composition for stereolithography 可乐丽则武齿科株式会社 2021-08-06 CN disclosed
EP-1315985-B1 PROCESS FOR SURFACE MODIFYING SUBSTRATES AND MODIFIED SUBSTRATES RESULTING THEREFROM NOVARTIS AG (CH) 2017-07-26 EP disclosed
EP-1377324-B1 COATED BIOMEDICAL DEVICES COMMW SCIENT IND RES ORG (AU) 2006-12-20 EP disclosed
US-7060288-B2 Biomedical devices COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2006-06-13 US disclosed
US-6893685-B2 Applying tie layer of polyionic material to surface; covalently binding bifunctional compound comprising ethylenically unsaturated double bond to the tie layer; graft polymerizing a hydrophilic monomer NOVARTIS AG (CH) 2005-05-17 US disclosed
EP-1377324-A1 COATED BIOMEDICAL DEVICES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-01-07 EP disclosed
EP-1315985-A2 PROCESS FOR SURFACE MODIFYING SUBSTRATES AND MODIFIED SUBSTRATES RESULTING THEREFROM Novartis AG (CH) 2003-06-04 EP disclosed
US-20020151972-A1 Biomedical devices COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2002-10-17 US disclosed
WO-2002068008-A1 COATED BIOMEDICAL DEVICES NOVARTIS PHARMA GMBH (AT) 2002-09-06 WO disclosed
US-20020086160-A1 Process for surface modifying substrates and modified substrates resulting therefrom ALCON INC. (CH) 2002-07-04 US disclosed
WO-2002016974-A2 PROCESS FOR SURFACE MODIFYING SUBSTRATES AND MODIFIED SUBSTRATES RESULTING THEREFROM NOVARTIS AG (CH) 2002-02-28 WO disclosed