SCHEMBL6018300

SCHEMBL6018300

O=C(ON1C(=O)CCC1=O)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 1/20 0.41
GMNN O75496 1/20 0.41
HTR3B O95264 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
MTOR P42345 1/20 0.41
HTR3A P46098 1/20 0.41
PMP22 Q01453 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TPMT P51580 1/20 0.41
MGLL Q99685 3/20 0.40
GAA P10253 1/20 0.40
POLB P06746 1/20 0.38
ALDH1A1 P00352 3/20 0.38
USP2 O75604 1/20 0.38
KMT2A Q03164 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13404895 0.87 MGLL (0.37) CYP1A2CYP2D6MGLLALDH1A1KMT2A
SCHEMBL1284517 0.83 TSHR (0.48) ALOX15TSHRGAAALDH1A1USP2
SCHEMBL7854466 0.82 MGLL (0.50) CYP1A2CYP2D6ALOX15TSHRMGLL
SCHEMBL2575973 0.80 CA12 (0.42) MGLLPOLBKMT2ATDP1
SCHEMBL13404894 0.80 CA12 (0.42) CYP1A2CYP2D6HSD17B10TPMTMGLL
SCHEMBL300884 0.79 CA12 (0.42) CYP1A2CYP2D6MGLLGAAALDH1A1
SCHEMBL17747110 0.79 CA12 (0.46) TSHRHSD17B10GAAPOLBALDH1A1
SCHEMBL22076666 0.79 MGLL (0.33) MGLLKMT2AMEN1HTT
SCHEMBL2575984 0.79 KDM4E (0.41) CYP1A2CYP2D6MGLLALDH1A1KMT2A
SCHEMBL2590087 0.79 NOTUM (0.36) MGLLPOLBALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7064234-B2 Enantioselective cation-exchange materials CHIRAL TECHNOLOGIES EUROPE SAS (FR) 2006-06-20 US disclosed
US-20050131087-A1 Enantioselective cation-exchange materials CHIRAL TECHNOLOGIES EUROPE SAS (FR) 2005-06-16 US disclosed