Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144844 | 0.88 | GALR3 (0.40) | DGAT1BRD4GALR3NR2F2LMNA | |
| SCHEMBL29835911 | 0.88 | GALR3 (0.40) | DGAT1BRD4GALR3NR2F2LMNA | |
| Dimethylamine SCHEMBL15212871 | 0.85 | GALR3 (0.38) | DGAT1BRD4GALR3NR2F2LMNA | |
| SCHEMBL13122602 | 0.79 | TDP1 (0.41) | DGAT1BRD4GALR3NR2F2LMNA | |
| SCHEMBL29985422 | 0.74 | KDM4E (0.45) | BRD4LMNAMAPTHSD17B10NPC1 | |
| SCHEMBL637860 | 0.73 | BRD4 (0.39) | BRD4GALR3NR2F2HSD17B10NPC1 | |
| SCHEMBL31709932 | 0.73 | TSHR (0.46) | DGAT1LMNAMAPTTSHRHSD17B10 | |
| SCHEMBL29991937 | 0.73 | ATM (0.47) | MAPTHSD17B10AKR1B10NPC1POLB | |
| SCHEMBL10004078 | 0.73 | DGAT1 (0.39) | DGAT1LMNAMAPTTSHRHSD17B10 | |
| SCHEMBL3297924 | 0.72 | DGAT1 (0.36) | DGAT1LMNAMAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613626-A1 | CYCLIC BENZIMIDAZOLES | ALTANA Pharma AG (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087701-A1 | CYCLIC BENZIMIDAZOLES | ALTANA PHARMA AG (DE) | 2004-10-14 | — | — | WO | disclosed |