Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018871 | 1.00 | ALDH1A1 (0.32) | ALDH1A1KMT2AMEN1TSHRHCAR2 | |
| SCHEMBL6018877 | 1.00 | ALDH1A1 (0.32) | ALDH1A1KMT2AMEN1TSHRHCAR2 | |
| SCHEMBL6019483 | 1.00 | ALDH1A1 (0.32) | ALDH1A1KMT2AMEN1TSHRHCAR2 | |
| SCHEMBL6018870 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL6018875 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL6018456 | 0.79 | KMT2A (0.33) | KMT2AHCAR2 | |
| SCHEMBL6018453 | 0.79 | KMT2A (0.33) | KMT2AHCAR2 | |
| SCHEMBL6018891 | 0.75 | NFKB1 (0.34) | HCAR2L3MBTL1 | |
| SCHEMBL6018882 | 0.75 | NFKB1 (0.34) | HCAR2L3MBTL1 | |
| SCHEMBL6018887 | 0.75 | NFKB1 (0.34) | HCAR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456171-B1 | SUBSTITUTED CYCLOHEXANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-12-20 | — | — | EP | disclosed |