Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3429735 | 0.93 | CHRNB2 (0.38) | CHRNB2CHRNA5CHRNA7CHRNA4SPHK2 | |
| SCHEMBL3429416 | 0.82 | F2RL3 (0.36) | F2RL3 | |
| SCHEMBL3429086 | 0.80 | ESR2 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL27221614 | 0.78 | PRKCA (0.38) | — | |
| SCHEMBL4032062 | 0.78 | SLC2A1 (0.36) | — | |
| SCHEMBL4032138 | 0.77 | PDE4D (0.38) | — | |
| SCHEMBL27221408 | 0.76 | PRKCA (0.37) | — | |
| SCHEMBL4314170 | 0.75 | PRMT5 (0.56) | PRMT5KLK7ALOX5APCHRNB2CHRNA5 | |
| SCHEMBL4314700 | 0.75 | PRMT5 (0.56) | PRMT5KLK7ALOX5APCHRNB2CHRNA5 | |
| SCHEMBL2895175 | 0.75 | PRMT5 (0.56) | PRMT5KLK7ALOX5APCHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270692-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270692-A1 | Chemical compounds | CCNI, MKI67, TP53 | PRMT5 1712/4885KLK7 2549/4885F2RL3 3957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.