SCHEMBL6021091

SCHEMBL6021091

COc1c(N=O)cccc1N(CCO)CCO

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
PABPC1 P11940 1/20 0.40
ALDH1A1 P00352 3/20 0.38
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
USP8 P40818 1/20 0.32
PRUNE1 Q86TP1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715199 0.79 MEN1 (0.47) MEN1KMT2APABPC1ALDH1A1GAA
SCHEMBL16026884 0.76 MEN1 (0.40) MEN1KMT2APABPC1ALDH1A1GAA
Hydrochloric Acid SCHEMBL29549392 0.75 MEN1 (0.39) MEN1KMT2APABPC1ALDH1A1GAA
Hydrochloric Acid SCHEMBL1116139 0.75 MEN1 (0.39) MEN1KMT2APABPC1ALDH1A1GAA
SCHEMBL1274323 0.74 KDM4E (0.40) ALDH1A1MAPT
SCHEMBL9015882 0.73 MEN1 (0.36) MEN1KMT2APABPC1ALDH1A1GAA
SCHEMBL13056776 0.70 CA1 (0.52) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL3779042 0.68 CA1 (0.44) MEN1KMT2APABPC1ALDH1A1GAA
SCHEMBL9461412 0.67 ALDH1A1 (0.37) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL179136 0.67 ALDH1A1 (0.43) MEN1KMT2AALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1639354-A1 TEST STRIP WITH SLOT VENT OPENING Roche Diagnostics GmbH (DE) 2006-03-29 EP disclosed
WO-2004113901-A1 TEST STRIP WITH SLOT VENT OPENING ROCHE DIAGNOSTICS GMBH (DE) 2004-12-29 WO disclosed