Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP8 | P40818 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29752123 | 1.00 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTTDP1KMT2A | |
| Hydrochloric Acid SCHEMBL29361270 | 0.98 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPTTDP1KMT2A | |
| Hydrochloric Acid SCHEMBL564874 | 0.98 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPTTDP1KMT2A | |
| SCHEMBL12377727 | 0.87 | CYBB (0.42) | ALDH1A1L3MBTL1 | |
| SCHEMBL23611530 | 0.85 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTTDP1KMT2A | |
| SCHEMBL30817926 | 0.85 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTTDP1KMT2A | |
| SCHEMBL11188554 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29914670 | 0.84 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11766454 | 0.83 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9527481 | 0.81 | SLC16A3 (0.49) | ALDH1A1L3MBTL1TDP1SLC16A3SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388824-B1 | METHODS OF DETECTING HIGH ANTIOXIDANT LEVELS DURING ELECTROCHEMICAL MEASUREMENTS AND FAILSAFING AN ANALYTE CONCENTRATION THEREFROM AS WELL AS DEVICES AND SYSTEMS INCORPORTING THE SAME | ROCHE DIABETES CARE GMBH (DE) | 2021-04-14 | — | — | EP | claimed |
| EP-2972269-B1 | METHODS OF DETECTING HIGH ANTIOXIDANT LEVELS DURING ELECTROCHEMICAL MEASUREMENTS AND FAILSAFING AN ANALYTE CONCENTRATION THEREFROM | ROCHE DIABETES CARE GMBH (DE) | 2018-07-11 | — | — | EP | claimed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | claimed |
| EP-1639355-B1 | METHOD FOR ANALYTE MEASUREMENT OF BIOLOGICAL FLUIDS USING DOSE SUFFICIENCY ELECTRODES | ROCHE DIABETES CARE GMBH (DE) | 2020-10-07 | — | — | EP | disclosed |
| EP-1639357-B1 | METHOD FOR DETERMINING AN ABUSED SENSOR DURING ANALYTE MEASUREMENT IN A BLOOD SAMPLE | ROCHE DIABETES CARE GMBH (DE) | 2019-08-07 | — | — | EP | disclosed |
| EP-1642123-B1 | METHOD FOR ANALYSIS OF A BIOLOGICAL FLUID BY THE USE OF ELECTRICAL MEANS | ROCHE DIABETES CARE GMBH (DE) | 2018-12-26 | — | — | EP | disclosed |
| EP-1642117-B1 | REAGENT STRIPE FOR TEST STRIP | ROCHE DIABETES CARE GMBH (DE) | 2018-06-13 | — | — | EP | disclosed |
| EP-2972268-B1 | METHODS OF FAILSAFING ELECTROCHEMICAL MEASUREMENTS OF AN ANALYTE AS WELL AS DEVICES, APPARATUSES AND SYSTEMS INCORPORATING THE SAME | ROCHE DIABETES CARE GMBH (DE) | 2017-05-24 | — | — | EP | disclosed |
| US-8962271-B2 | Fructosyl peptidyl oxidase | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-8859293-B2 | Method for determining whether a disposable, dry regent, electrochemical test strip is unsuitable for use | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2014-10-14 | — | — | US | disclosed |
| EP-2462239-B1 | Fructosyl peptidyl oxidase and sensor for assaying a glycated protein | ROCHE DIAGNOSTICS GMBH (DE) | 2014-09-17 | — | — | EP | disclosed |
| US-20040157338-A1 | System and method for determining a temperature during analyte measurement | ROCHE DIABETES CARE, INC. | 2004-08-12 | — | — | US | disclosed |
| US-20040157337-A1 | System and method for analyte measurement using AC phase angle measurements | ROCHE DIABETES CARE, INC. | 2004-08-12 | — | — | US | disclosed |
| US-20040157339-A1 | System and method for analyte measurement using AC excitation | ROCHE DIABETES CARE, INC. | 2004-08-12 | — | — | US | disclosed |
| EP-0441222-B1 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1996-12-18 | — | — | EP | disclosed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5122244-A | Having a reducible nitroso or oxime compound to transfer electrons leading to a signal and form an aromatic amine oxidizable to a compound different from the original; low voltage | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-16 | — | — | US | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4093806-A | HAIR DYES | L'OREAL (FR) | 1978-06-06 | — | — | US | disclosed |
| US-4046786-A | HAIR DYES | L'OREAL (FR) | 1977-09-06 | — | — | US | disclosed |