Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138040 | 0.85 | TACR1 (0.49) | TACR1TACR3 | |
| SCHEMBL3479999 | 0.83 | MAPK9 (0.62) | TACR1MAPK9MAPK10TACR3 | |
| SCHEMBL7139305 | 0.79 | MAPK14 (0.43) | MAPK9MAPK10MMP2MMP13 | |
| SCHEMBL7139566 | 0.78 | KDM4E (0.42) | MAPK9MAPK10 | |
| SCHEMBL7149127 | 0.78 | MEN1 (0.52) | — | |
| SCHEMBL6021542 | 0.77 | CXCR3 (0.42) | MAPK9MAPK10 | |
| SCHEMBL7142563 | 0.77 | TP53 (0.44) | — | |
| SCHEMBL7139598 | 0.76 | BCHE (0.44) | — | |
| SCHEMBL7139690 | 0.76 | IDO1 (0.38) | MAPK9MAPK10 | |
| SCHEMBL6021596 | 0.75 | ALDH1A1 (0.41) | MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663193-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-07 | — | — | EP | claimed |
| WO-2005025558-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | APPLIED RESERACH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | claimed |