Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251719 | 1.00 | MEN1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL21657309 | 1.00 | MEN1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL10009389 | 0.97 | ALDH1A1 (0.57) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL4395129 | 0.97 | ALDH1A1 (0.57) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL9007891 | 0.97 | ALDH1A1 (0.57) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL3060254 | 0.95 | ALDH1A1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL10936372 | 0.95 | ALDH1A1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL271637 | 0.95 | ALDH1A1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL427388 | 0.95 | — | — | |
| SCHEMBL10941081 | 0.95 | ALDH1A1 (0.60) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8834934-B2 | Material encapsulation system | HAVILAND PRODUCTS COMPANY (US) | 2014-09-16 | — | — | US | claimed |
| US-20060110464-A1 | Material encapsulation system | HAVILAND PRODUCTS COMPANY | 2006-05-25 | — | — | US | claimed |
| EP-1596831-A2 | MATERIAL INCAPSULATION SYSTEM | Venture Management Alliance, LLC (US) | 2005-11-23 | — | — | EP | claimed |
| WO-2004073033-A2 | MATERIAL INCAPSULATION SYSTEM | VENTURE MANAGEMENT ALLIANCE, LLC (US) | 2004-08-26 | — | — | WO | claimed |
| US-9500653-B2 | Small-molecule hydrophobic tagging of fusion proteins and induced degradation of same | YALE UNIVERSITY (US) | 2016-11-22 | — | — | US | disclosed |
| US-20140364352-A1 | Material Release System | HAVILAND PRODUCTS COMPANY (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140302523-A1 | Small-Molecule Hydrophobic Tagging of Fusion Proteins and Induced Degradation of Same | YALE UNIVERSITY (US) | 2014-10-09 | — | — | US | disclosed |
| US-8834934-B2 | Material encapsulation system | HAVILAND PRODUCTS COMPANY (US) | 2014-09-16 | — | — | US | disclosed |
| US-20060110464-A1 | Material encapsulation system | HAVILAND PRODUCTS COMPANY | 2006-05-25 | — | — | US | disclosed |
| EP-1596831-A2 | MATERIAL INCAPSULATION SYSTEM | Venture Management Alliance, LLC (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004073033-A2 | MATERIAL INCAPSULATION SYSTEM | VENTURE MANAGEMENT ALLIANCE, LLC (US) | 2004-08-26 | — | — | WO | disclosed |