Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10009389 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ATHRBHTT | |
| SCHEMBL21657309 | 0.97 | MEN1 (0.60) | ALDH1A1MEN1KMT2ATHRBHTT | |
| SCHEMBL11251719 | 0.97 | MEN1 (0.60) | ALDH1A1MEN1KMT2ATHRBHTT | |
| SCHEMBL6021998 | 0.97 | MEN1 (0.60) | ALDH1A1MEN1KMT2ATHRBHTT | |
| SCHEMBL3060254 | 0.97 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ATHRBHTT | |
| SCHEMBL10941081 | 0.97 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ATHRBHTT | |
| SCHEMBL427388 | 0.97 | — | — | |
| SCHEMBL4335363 | 0.97 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ATHRBHTT | |
| SCHEMBL2952922 | 0.97 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ATHRBHTT | |
| SCHEMBL10936372 | 0.97 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571689-A | Method of N-acylating peptide and proteins with diheteroatom substituted analogs of myristic acid | WASHINGTON UNIVERSITY (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0441765-B1 | Novel fatty acid analog enzyme substrates | UNIV WASHINGTON (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5082967-A | Myristolyation | WASHINGTON UNIVERSITY (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0441765-A1 | Novel fatty acid analog enzyme substrates | WASHINGTON UNIVERSITY (US) | 1991-08-14 | — | — | EP | disclosed |