SCHEMBL6022352

SCHEMBL6022352

CC(C)CCNS(=O)(=O)c1ccc2[nH]c(=O)cc(C(F)(F)F)c2c1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 18/20 0.56
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6022505 0.89 AR (0.64) ARPOLB
SCHEMBL6022627 0.87 AR (0.65) ARPOLB
SCHEMBL6022533 0.85 AR (0.55) ARPOLB
SCHEMBL6022437 0.84 AR (0.52) ARPOLB
SCHEMBL6023691 0.84 AR (0.58) ARPOLB
SCHEMBL6022560 0.84 ALDH1A1 (0.49) ARPOLB
SCHEMBL6022504 0.83 AR (0.57) ARPOLB
SCHEMBL6022466 0.83 AR (0.52) ARPOLB
SCHEMBL6022460 0.82 AR (0.62) AR
SCHEMBL6023797 0.82 PARP1 (0.53) ARPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7009052-B2 Sulfonamide derivatives WARNER LAMBERT COMPANY LLC (US) 2006-03-07 US disclosed