Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 16/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022130 | 0.92 | PARP1 (0.64) | PARP1ARPOLBPKM | |
| SCHEMBL5761270 | 0.90 | AR (0.48) | PARP1ARPOLBPKM | |
| SCHEMBL6022505 | 0.88 | AR (0.64) | ARPOLB | |
| SCHEMBL6023726 | 0.85 | AR (0.52) | ARPOLBPKM | |
| SCHEMBL6023094 | 0.83 | POLB (0.71) | ARPOLBPKMLMNA | |
| SCHEMBL5761611 | 0.82 | PARP1 (0.53) | PARP1ARPOLBPKM | |
| SCHEMBL6022352 | 0.82 | AR (0.56) | ARPOLB | |
| SCHEMBL6023623 | 0.81 | PKM (0.70) | ARPOLBPKM | |
| SCHEMBL6022445 | 0.81 | POLB (0.56) | ARPOLBPKMLMNA | |
| SCHEMBL6022627 | 0.80 | AR (0.65) | ARPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |