Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996208 | 0.82 | TSHR (0.30) | TSHR | |
| SCHEMBL9343883 | 0.79 | — | — | |
| SCHEMBL706106 | 0.77 | — | — | |
| SCHEMBL1127828 | 0.77 | — | — | |
| SCHEMBL9491619 | 0.77 | — | — | |
| SCHEMBL18414215 | 0.77 | — | — | |
| SCHEMBL7990640 | 0.77 | — | — | |
| SCHEMBL4582841 | 0.76 | LMNA (0.36) | — | |
| SCHEMBL7992456 | 0.73 | — | — | |
| SCHEMBL891346 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165648-B1 | HEAT-CURABLE COATING AGENT AND ITS USE | BASF Aktiengesellschaft (DE) | 1989-11-29 | — | — | EP | claimed |
| US-4777194-A | BLEND OF A POLYEPOXIDE-AMINE AND PHENOLIC RESIN | BASF AKTIENGESELLSCHAFT (DE) | 1988-10-11 | — | — | US | claimed |
| US-20240197661-A1 | ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF | HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT | 2024-06-20 | — | — | US | disclosed |
| US-20240024249-A1 | ORAL DOSAGE FORMS HAVING A HIGH LOADING OF A METHYL HYDROGEN FUMARATE PRODRUG | HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT | 2024-01-25 | — | — | US | disclosed |
| CN-112920066-A | Alpha-substituted-alpha-amino acid ester compound and preparation method thereof | 华南理工大学 | 2021-06-08 | — | — | CN | disclosed |
| US-20210145755-A1 | ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF | ARBOR PHARMACEUTICALS, LLC | 2021-05-20 | — | — | US | disclosed |
| US-10940117-B2 | Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof | ARBOR PHARMACEUTICALS, LLC (US) | 2021-03-09 | — | — | US | disclosed |
| US-20200246271-A1 | ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF | HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT | 2020-08-06 | — | — | US | disclosed |
| US-10716760-B2 | Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof | ARBOR PHARMACEUTICALS, LLC (US) | 2020-07-21 | — | — | US | disclosed |
| US-20170157056-A9 | ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF | XENOPORT, INC. (US) | 2017-06-08 | — | — | US | disclosed |
| US-9597292-B2 | Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof | XENOPORT, INC. (US) | 2017-03-21 | — | — | US | disclosed |
| EP-0894261-A1 | COVALENTLY IMMOBILIZED FLUOROIONOPHORES AS OPTICAL ION SENSORS | Novartis AG (CH) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997039337-A1 | COVALENTLY IMMOBILIZED FLUOROIONOPHORES AS OPTICAL ION SENSORS | NOVARTIS AG (CH) | 1997-10-23 | — | — | WO | disclosed |
| EP-0209023-B1 | MODIFIED PHENOL RESINS, PROCESS FOR THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1990-05-09 | — | — | EP | disclosed |
| US-4777194-A | BLEND OF A POLYEPOXIDE-AMINE AND PHENOLIC RESIN | BASF AKTIENGESELLSCHAFT (DE) | 1988-10-11 | — | — | US | disclosed |
| US-4777194-A | BLEND OF A POLYEPOXIDE-AMINE AND PHENOLIC RESIN | BASF AKTIENGESELLSCHAFT (DE) | 1988-10-11 | — | — | US | disclosed |
| US-4675375-A | Preparation of phenol resol ethers bonded via o,o'-methylene ether groups | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-23 | — | — | US | disclosed |
| EP-0209023-A2 | Modified phenol resins, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1987-01-21 | — | — | EP | disclosed |
| US-4455342-A | REINFORCEMENT OF TEXTILES | ROHM GMBH (DE) | 1984-06-19 | — | — | US | disclosed |
| US-4064110-A | FROM 5-ALKOXYMETHYL-1,3,4-DIOXAZOL-2-ONES, ALKALI METAL CARBOXYLATE CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1977-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200246271-A1 | ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF | FH, MGMT, BHMT2 | TSHR 4205/4885 |
| US-20210145755-A1 | ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF | FH, MGMT, BHMT2 | TSHR 4205/4885 |
| US-20240024249-A1 | ORAL DOSAGE FORMS HAVING A HIGH LOADING OF A METHYL HYDROGEN FUMARATE PRODRUG | FH, MGMT, CYP4F2 | TSHR 4391/4885 |
| US-20170157056-A9 | ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF | FH, MGMT, BHMT2 | TSHR 4205/4885 |
| US-20240197661-A1 | ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF | MGMT, MTHFD2, PHF2 | TSHR 4207/4885 |
| US-10940117-B2 | Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof | FH, MGMT, BHMT2 | TSHR 4205/4885 |
| US-10716760-B2 | Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof | FH, MGMT, BHMT2 | TSHR 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.