Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022869 | 0.87 | ACHE (0.55) | ACHE | |
| SCHEMBL6022672 | 0.86 | ACHE (0.54) | MAPTSMN1; SMN2LMNAACHEALDH1A1 | |
| SCHEMBL6022682 | 0.80 | MAPT (0.45) | MAPTSMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL6022932 | 0.79 | MAPT (0.57) | MAPTSMN1; SMN2LMNAACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL6024148 | 0.76 | MAPT (0.43) | MAPTSMN1; SMN2LMNAACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL6024131 | 0.75 | MAPT (0.45) | MAPTSMN1; SMN2LMNAACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL6024133 | 0.75 | MAPT (0.45) | MAPTSMN1; SMN2LMNAACHEALDH1A1 | |
| SCHEMBL6023352 | 0.72 | ACHE (0.45) | ACHEALDH1A1POLB | |
| SCHEMBL6023056 | 0.72 | ACHE (0.54) | ACHE | |
| SCHEMBL6022503 | 0.72 | ACHE (0.44) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078407-B2 | 4-hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-07-18 | — | — | US | disclosed |
| US-20030162789-A1 | 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162789-A1 | 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them | HTT, PARK7, NQO1 | MAPT 69/4885SMN1; SMN2 140/4885LMNA 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.