SCHEMBL6022941

SCHEMBL6022941

CCC(CC)Oc1cc(/C=C/C(=O)Nc2cccc(O)c2)cc(OC(CC)CC)c1O

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 17/20 0.62
MMP2 P08253 17/20 0.62
MMP9 P14780 17/20 0.62
MAOB P27338 3/20 0.53
KDM1A O60341 1/20 0.49
MEN1 O00255 1/20 0.47
NPC1 O15118 1/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
NFKB1 P19838 1/20 0.47
RAB9A P51151 1/20 0.47
NFKB2 Q00653 1/20 0.47
KMT2A Q03164 1/20 0.47
RELA Q04206 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6022945 1.00 MMP1 (0.62) MMP1MMP2MMP9MAOBKDM1A
SCHEMBL6023357 0.90 KDM1A (0.57) MMP1MMP2MMP9MAOBKDM1A
SCHEMBL6023356 0.90 KDM1A (0.57) MMP1MMP2MMP9MAOBKDM1A
SCHEMBL6022727 0.81 KDM1A (0.60) MMP1MMP2MMP9KDM1AMEN1
SCHEMBL6022726 0.81 KDM1A (0.60) MMP1MMP2MMP9KDM1AMEN1
SCHEMBL6022688 0.81 MMP1 (0.59) MMP1MMP2MMP9MAOB
SCHEMBL6022690 0.81 MMP1 (0.59) MMP1MMP2MMP9MAOB
SCHEMBL28316655 0.78 MMP1 (1.00) MMP1MMP2MMP9MAOB
SCHEMBL6022720 0.76 KDM1A (0.54) MMP1MMP2MMP9MAOBKDM1A
SCHEMBL6022715 0.76 KDM1A (0.54) MMP1MMP2MMP9MAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030162789-A1 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2003-08-28 US claimed
US-7078407-B2 4-hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2006-07-18 US disclosed
US-20030162789-A1 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2003-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162789-A1 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them HTT, PARK7, NQO1 MMP1 2333/4885MMP2 1455/4885MMP9 862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.