⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66146 | 0.90 | — | — | |
| SCHEMBL6974870 | 0.88 | — | — | |
| SCHEMBL7739600 | 0.88 | — | — | |
| SCHEMBL7738671 | 0.88 | — | — | |
| SCHEMBL649143 | 0.69 | — | — | |
| SCHEMBL4939813 | 0.65 | — | — | |
| SCHEMBL6168487 | 0.62 | — | — | |
| SCHEMBL101996 | 0.60 | — | — | |
| SCHEMBL8790789 | 0.60 | — | — | |
| SCHEMBL7075091 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167489-B1 | PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS | SUNESIS PHARMACEUTICALS INC (US) | 2017-05-03 | — | — | EP | claimed |
| EP-2362218-B1 | METHODS OF MONITORING THE EFFICACY OF FARNESYLTRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-27 | — | — | EP | claimed |
| US-8802657-B2 | Compounds useful as Raf kinase inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-08-12 | — | — | US | claimed |
| US-20130065858-A1 | COMPOUNDS USEFUL AS RAF KINASE INHIBITORS | SUNESIS PHARMACEUTICALS, INC. (US) | 2013-03-14 | — | — | US | claimed |
| EP-1664062-B1 | ISOTHIAZOLOQUINOLONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS | ACHILLION PHARMACEUTICALS INC (US) | 2013-03-13 | — | — | EP | claimed |
| EP-2167489-A2 | PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS | Sunesis Pharmaceuticals, Inc. (US) | 2010-03-31 | — | — | EP | claimed |
| US-20090036419-A1 | COMPOUNDS USEFUL AS RAF KINASE INHIBITORS | SUNESIS PHARMACEUTICALS, INC. (US) | 2009-02-05 | — | — | US | claimed |
| WO-2009006389-A2 | PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS | SUNESIS PHARMACEUTICALS, INC. (US) | 2009-01-08 | — | — | WO | claimed |
| US-20080119467-A1 | Purine Derivatives, Compositions Containing Them and Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-05-22 | — | — | US | claimed |
| EP-1809846-B1 | METHOD FOR MAKING SECURE VALUABLE DOCUMENTS | FRANCOIS CHARLES OBERTHUR FIDU (FR) | 2008-02-20 | — | — | EP | claimed |
| WO-2006042967-A1 | METHOD FOR MAKING SECURE VALUABLE DOCUMENTS | FRANÇOIS CHARLES OBERTHUR FIDUCIAIRE (SA) (FR) | 2006-04-27 | — | — | WO | claimed |
| EP-1200433-B1 | C-6 RING-SUBSTITUTED PYRIDO[1,2-a]BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS | ORTHO MCNEIL PHARM INC (US) | 2006-03-22 | — | — | EP | claimed |
| WO-2005021003-A2 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA BIOSCIENCE NV (BE) | 2005-03-10 | — | — | WO | claimed |
| US-20040077859-A1 | Immunosuppressive effects of pteridine derivatives | 4 AZA BIOSCIENCE NV (BE) | 2004-04-22 | — | — | US | claimed |
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | claimed |
| US-20030236255-A1 | Immunosuppressive effects of pteridine derivatives | 4 AZA BIOSCIENCE NV (BE) | 2003-12-25 | — | — | US | claimed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | claimed |
| EP-0606046-B1 | Arylsulfonamido-substituted hydroxamic acids | CIBA GEIGY AG (CH) | 1997-10-08 | — | — | EP | claimed |
| US-4908359-A | Pharmaceuticals | Uclaf, Roussel (FR) | 1990-03-13 | — | — | US | claimed |
| EP-0114850-B1 | NEW SUBSTITUTED DERIVATIVES OF 2,5-DIAMINO 1,4-DIAZOLE, PREPARATION METHODS THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOUCHARA S.A. (FR) | 1988-06-29 | — | — | EP | claimed |