SCHEMBL66146

SCHEMBL66146

S=C1[CH]CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5695351 0.97
SCHEMBL7739600 0.97
SCHEMBL6974870 0.97
SCHEMBL7738671 0.97
SCHEMBL602295 0.90
SCHEMBL9170284 0.69
SCHEMBL18931046 0.69 ALDH1A1 (0.39)
SCHEMBL100581 0.62
SCHEMBL5244074 0.62
SCHEMBL65251 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 851 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228491-A1 METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SCINNOHUB PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 US claimed
EP-4332101-A1 METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2024-03-06 EP claimed
WO-2022257351-A1 POLYDISULFIDE MATERIAL HAVING EXCELLENT OPTICAL PROPERTIES AND PREPARATION METHOD THEREFOR 大连理工大学 2022-12-15 WO claimed
EP-3904443-A1 LIGHT-RESISTANT, HEAT-RESISTANT, AND DURABLE UV ABSORBENT Miyoshi Oil & Fat Co., Ltd. (JP) 2021-11-03 EP claimed
CN-113272263-A Glass plate with coating film and composition for forming the same 日本板硝子株式会社 2021-08-17 CN claimed
CN-113195611-A Light-resistant, heat-resistant and durable ultraviolet absorber 三吉油脂株式会社 2021-07-30 CN claimed
WO-2020137819-A1 LIGHT-RESISTANT, HEAT-RESISTANT, AND DURABLE UV ABSORBENT ミヨシ油脂株式会社 2020-07-02 WO claimed
CN-111057048-A Aminopyrazine/pyridine compound, preparation method and application 如东凌达生物医药科技有限公司 2020-04-24 CN claimed
EP-2167489-B1 PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS SUNESIS PHARMACEUTICALS INC (US) 2017-05-03 EP claimed
US-8802657-B2 Compounds useful as Raf kinase inhibitors MILLENNIUM PHARMACEUTICALS, INC. (US) 2014-08-12 US claimed
EP-0922030-A1 ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1999-06-16 EP claimed
EP-0895988-A1 Arylsulfonylamino hydroxamic acid derivatives Pfizer Products Inc. (US) 1999-02-10 EP claimed
US-5863949-A Arylsulfonylamino hydroxamic acid derivatives PFIZER INC (US) 1999-01-26 US claimed
US-5861510-A Arylsulfonyl hydroxamic acid derivatives as MMP and TNF inhibitors PFIZER INC (US) 1999-01-19 US claimed
WO-1998034918-A1 ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1998-08-13 WO claimed
WO-1998007697-A1 ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1998-02-26 WO claimed
EP-0821671-A1 ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES AS MMP AND TNF INHIBITORS PFIZER INC. (US) 1998-02-04 EP claimed
EP-0813520-A1 ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1997-12-29 EP claimed
WO-1996033172-A1 ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES AS MMP AND TNF INHIBITORS PFIZER INC. (US) 1996-10-24 WO claimed
WO-1996027583-A1 ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1996-09-12 WO claimed