Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARG | Q86W56 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022484 | 0.84 | ALDH1A1 (0.62) | PKMALDH1A1LMNAKDM4ETAAR1 | |
| SCHEMBL6022506 | 0.81 | MEN1 (0.56) | MEN1KMT2A | |
| SCHEMBL6022517 | 0.81 | TP53 (0.49) | ALOX15TP53ALDH1A1HTR6CA12 | |
| SCHEMBL6023202 | 0.81 | PARG (0.52) | PKMALDH1A1KMT2APARGLMNA | |
| SCHEMBL6022155 | 0.81 | ALDH1A1 (0.54) | PKMTP53ALDH1A1PARGLMNA | |
| SCHEMBL6022426 | 0.79 | PARG (0.52) | PKMALDH1A1MEN1KMT2APARG | |
| SCHEMBL6022490 | 0.78 | PARG (0.46) | TP53ALDH1A1PARGLMNAKDM4E | |
| SCHEMBL6023756 | 0.77 | MAPK1 (0.47) | TP53ALDH1A1PARGLMNAHSD17B10 | |
| SCHEMBL6022235 | 0.75 | TAS2R14 (0.47) | PKMTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL6022431 | 0.74 | BRD1 (0.61) | PKMTP53MEN1KMT2APARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |