Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GLUL | P15104 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27195667 | 1.00 | GRIK1 (0.42) | GRIK1GRIK2GRM1GRM2GLUL | |
| SCHEMBL2265288 | 0.85 | GRIK1 (0.43) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL1891190 | 0.83 | GRIK1 (0.42) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL9807834 | 0.83 | CA4 (0.39) | — | |
| SCHEMBL771737 | 0.83 | CA4 (0.39) | — | |
| SCHEMBL28132439 | 0.81 | GRIK1 (0.41) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL49769 | 0.80 | GRM8 (0.52) | GRIK1GRIK2GRM1GRM2GLUL | |
| SCHEMBL213854 | 0.80 | GRM8 (0.52) | GRIK1GRIK2GRM1GRM2GLUL | |
| SCHEMBL213855 | 0.80 | GRM8 (0.52) | GRIK1GRIK2GRM1GRM2GLUL | |
| Aspartic Acid SCHEMBL28664670 | 0.79 | CA4 (0.56) | GRIK1GRIK2GRM1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 588 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220260583-A1 | CHEMOPROTEOMIC PROFILING OF PROTEIN ELECTROPHILIC AND OXIDATIVE POST-TRANSLATIONAL MODIFICATIONS | Zenagem, LLC | 2022-08-18 | — | — | US | claimed |
| EP-3986919-A1 | PROCESS FOR THE MANUFACTURE OF GLUCAGON | Fresenius Kabi iPSUM S.r.l. (IT) | 2022-04-27 | — | — | EP | claimed |
| US-11226337-B2 | Chemoproteomic profiling of protein electrophilic and oxidative post-translational modifications | Zenagem, LLC (US) | 2022-01-18 | — | — | US | claimed |
| US-10568854-B2 | Compositions and methods for treating kabuki syndrome and related disorders | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-02-25 | — | — | US | claimed |
| US-20190204336-A1 | CHEMOPROTEOMIC PROFILING OF PROTEIN ELECTROPHILIC AND OXIDATIVE POST-TRANSLATIONAL MODIFICATIONS | Zenagem, LLC | 2019-07-04 | — | — | US | claimed |
| EP-2851421-B1 | USEFUL MICROORGANISM, AND METHOD FOR PRODUCING SUBSTANCE OF INTEREST | KAO CORP (JP) | 2018-11-28 | — | — | EP | claimed |
| US-20170100354-A1 | COMPOSITIONS AND METHODS FOR TREATING KABUKI SYNDROME AND RELATED DISORDERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-04-13 | — | — | US | claimed |
| CN-103384809-B | For method and the component of thermal energy storage | Renewable Energy System Technology (TFRES) SDN BHD (BE) | 2016-01-20 | — | — | CN | claimed |
| WO-2015184279-A1 | COMPOSITIONS AND METHODS FOR TREATING KABUKI SYNDROME AND RELATED DISORDERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-12-03 | — | — | WO | claimed |
| CN-104379729-A | Useful microorganism, and method for producing desired substance | GENARIS INC | 2015-02-25 | — | — | CN | claimed |
| US-20130209433-A1 | MODULATION OF AMINO ACID METABOLISM IN THE HYPOTHALAMUS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-08-15 | — | — | US | claimed |
| US-8494779-B2 | Method for screening essential metabolites in growth of microorganisms | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | claimed |
| US-20100143911-A1 | METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-06-10 | — | — | US | claimed |
| US-20100104548-A1 | MODULATION OF AMINO ACID METABOLISM IN THE HYPOTHALAMUS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-04-29 | — | — | US | claimed |
| EP-2097743-A1 | METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS | Korea Advanced Institute of Science and Technology (KR) | 2009-09-09 | — | — | EP | claimed |
| WO-2008078911-A1 | METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-07-03 | — | — | WO | claimed |
| WO-2007002365-A2 | MODULATION OF AMINO ACID METABOLISM IN THE HYPOTHALAMUS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2007-01-04 | — | — | WO | claimed |
| US-6495356-B1 | BERYLLIUM ATOM IS COMPLEXED WITH FLUORINE LIGANDS IN LIEU OF A PHOSPHATE GROUP AT PHOSPHORYLATION SITE; BEFX REACTS WITH CARBOXYL GROUP TO MIMIC AN ACYL PHOSPHATE LINKAGE; FORMED IN THE SUBSTANTIAL ABSENCE OF A NUCLEOSIDE PHOSPHATE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-12-17 | — | — | US | claimed |
| WO-2001040268-A2 | BERYLLOFLUORIDE ANALOGUES OF ACYL PHOSPHATE POLYPEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-06-07 | — | — | WO | claimed |
| WO-1998044148-A1 | HISTIDINE KINASE ASSAY | MYCOTOX, INC. (US) | 1998-10-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190204336-A1 | CHEMOPROTEOMIC PROFILING OF PROTEIN ELECTROPHILIC AND OXIDATIVE POST-TRANSLATIONAL MODIFICATIONS | PTMS, CHAMP1, STUB1 | GRIK1 3131/4885GRIK2 3273/4885GRM1 2551/4885 |
| US-11226337-B2 | Chemoproteomic profiling of protein electrophilic and oxidative post-translational modifications | PTMS, CHAMP1, STUB1 | GRIK1 3131/4885GRIK2 3273/4885GRM1 2551/4885 |
| US-20220260583-A1 | CHEMOPROTEOMIC PROFILING OF PROTEIN ELECTROPHILIC AND OXIDATIVE POST-TRANSLATIONAL MODIFICATIONS | STUB1, PTMS, TMT1A | GRIK1 2999/4885GRIK2 3031/4885GRM1 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.