Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL4775933 | 0.85 | GRM8 (0.40) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL27759943 | 0.85 | GRM8 (0.40) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aminocarbonyl Dihydrogen Phosphate SCHEMBL21410683 | 0.84 | CA4 (0.50) | CA4GRM8GRM6GRM7GRM4 | |
| Aspartic Acid SCHEMBL23362892 | 0.82 | GRM8 (0.43) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL3379838 | 0.82 | GRM8 (0.48) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL3379835 | 0.82 | GRM8 (0.48) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL1891184 | 0.80 | GRM8 (0.47) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL1891183 | 0.80 | GRM8 (0.47) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL8087513 | 0.79 | GRIK1 (0.54) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL8087511 | 0.79 | GRIK1 (0.54) | GRM8GRM6GRM7GRM4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113755416-B | Recombinant microorganism having novel synthetic pathway for producing beta-thymidine and method for producing beta-thymidine | 苏州华赛生物工程技术有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-113755416-A | Recombinant microorganism with novel synthetic pathway for producing beta-thymidine and method for producing beta-thymidine | 苏州华赛生物工程技术有限公司 | 2021-12-07 | — | — | CN | disclosed |