⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39040 | 0.76 | — | — | |
| SCHEMBL25557 | 0.76 | — | — | |
| Hydrogen Sulfide SCHEMBL28083346 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL19925359 | 0.72 | — | — | |
| SCHEMBL14681010 | 0.71 | — | — | |
| SCHEMBL538316 | 0.71 | — | — | |
| SCHEMBL1405883 | 0.71 | — | — | |
| SCHEMBL18277306 | 0.69 | — | — | |
| SCHEMBL1217198 | 0.67 | — | — | |
| SCHEMBL3343002 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12636385-B2 | Selective ligands for tau aggregates | SENTONIX, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| US-20210138092-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | CBD SOLUTIONS AB (SE) | 2021-05-13 | — | — | US | disclosed |
| EP-3774771-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | Karin&Sten Mortstedt CBD Solutions AB (SE) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019197502-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) | 2019-10-17 | — | — | WO | disclosed |
| US-20100272642-A1 | PET PROBE HAVING AN ALKOXY GROUP SUBSTITUTED BY FLUORINE AND HYDROXY GROUP | TOHOKU UNIVERSITY (JP) | 2010-10-28 | — | — | US | disclosed |
| US-20100272642-A1 | PET PROBE HAVING AN ALKOXY GROUP SUBSTITUTED BY FLUORINE AND HYDROXY GROUP | TOHOKU UNIVERSITY (JP) | 2010-10-28 | — | — | US | disclosed |
| US-7129259-B2 | Halogenated biaryl heterocyclic compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. (US) | 2006-10-31 | — | — | US | disclosed |
| EP-1713785-A1 | HALOGENATED BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | Rib-X Pharmaceuticals, Inc. (US) | 2006-10-25 | — | — | EP | disclosed |
| US-20060148869-A1 | Halogenated biaryl heterocyclic compounds and methods of making and using the same | CHEN SHILI | 2006-07-06 | — | — | US | disclosed |
| US-20050153971-A1 | Halogenated biaryl heterocyclic compounds and methods of making and using the same | MELINTA SUBSIDIARY CORP. | 2005-07-14 | — | — | US | disclosed |
| WO-2005061468-A1 | HALOGENATED BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2005-07-07 | — | — | WO | disclosed |
| CN-1193963-A | Aromatic compounds and pharmaceutical compositions containing them | ZENECA LTD (GB) | 1998-09-23 | — | — | CN | disclosed |