⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1217198 | 1.00 | — | — | |
| SCHEMBL3343095 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL4617478 | 0.96 | — | — | |
| 1,3-Butanediol SCHEMBL11167714 | 0.81 | THRB (0.50) | — | |
| SCHEMBL25557 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL19925359 | 0.75 | — | — | |
| Glycerin SCHEMBL10453101 | 0.74 | LMNA (1.00) | — | |
| Glycerin SCHEMBL3418854 | 0.74 | LMNA (1.00) | — | |
| Glycerin SCHEMBL8080917 | 0.74 | LMNA (1.00) | — | |
| Glycerin SCHEMBL14278797 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368627-A1 | PYRAZOLESULFONAMIDES AS ANTITUMOR AGENTS | Peloton Therapeutics, Inc., a fully owned subsidiary of Merck Sharp & Dohme LLC (US) | 2025-12-04 | — | — | US | disclosed |
| CN-111909173-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-3953331-B1 | PYRAZOLESULFONAMIDES AS ANTITUMOR AGENTS | PELOTON THERAPEUTICS INC (US) | 2024-11-20 | — | — | EP | disclosed |
| CN-112047960-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-112062778-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-11553713-B2 | Polyalcohol, carbohydrate, nucleobase and nucleotide compositions and uses thereof | Zhang, Chunbo (US) | 2023-01-17 | — | — | US | disclosed |
| US-20220162193-A1 | PYRAZOLESULFONAMIDES AS ANTITUMOR AGENTS | PELOTON THERAPEUTICS, INC. (US) | 2022-05-26 | — | — | US | disclosed |
| CN-108697077-B | Polyol, carbohydrate, nucleobase and nucleoside compositions and uses thereof | 组合块公司 | 2022-04-19 | — | — | CN | disclosed |
| EP-3953331-A1 | PYRAZOLESULFONAMIDES AS ANTITUMOR AGENTS | Peloton Therapeutics, Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| WO-2020210139-A1 | PYRAZOLESULFONAMIDES AS ANTITUMOR AGENTS | PELOTON THERAPEUTICS, INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| US-20200236932-A1 | POLYALCOHOL, CARBOHYDRATE, NUCLEOBASE AND NUCLEOTIDE COMPOSITIONS AND USES THEREOF | ZHANG, CHUNBO | 2020-07-30 | — | — | US | disclosed |
| WO-2017053467-A1 | POLYALCOHOL, CARBOHYDRATE, NUCLEOBASE AND NUCLEOSIDE COMPOSITIONS AND USES THEREOF | COMBI-BLOCKS, INC. (US) | 2017-03-30 | — | — | WO | disclosed |
| WO-2012150220-A1 | RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-11-08 | — | — | WO | disclosed |
| EP-2364973-A1 | Heterocyclic inhibitors of MEK and Methods of use thereof | Array Biopharma, Inc. (US) | 2011-09-14 | — | — | EP | disclosed |
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | EXELIXIS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| EP-1967516-B1 | 4-(phenylamino)-6-oxo-1,6-dihydropyridazine-3-carboxamide derivatives as MEK inhibitors for the treatment of hyperproliferative diseases | ARRAY BIOPHARMA INC (US) | 2009-11-04 | — | — | EP | disclosed |
| WO-2007044084-A2 | HETEROCYCLIC INHIBITORS OF MEK AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2007-04-19 | — | — | WO | disclosed |
| US-5846793-A | Microbial process for biotransformation to (R)-3-chloro-1,2-propanediol | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-12-08 | — | — | US | disclosed |
| EP-0286059-B1 | PROCESS FOR PREPARING (R)-3-CHLORO-1, 2-PROPANEDIOL | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-01 | — | — | EP | disclosed |
| EP-0286059-A1 | Process for preparing (R)-3-Chloro-1, 2-Propanediol | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-10-12 | — | — | EP | disclosed |