Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BMP1 | P13497 | 7/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024626 | 0.82 | BMP1 (0.47) | GAARAB9ABMP1KDM4EHTT | |
| SCHEMBL6023388 | 0.77 | BMP1 (0.44) | BMP1MMP12 | |
| SCHEMBL6024200 | 0.75 | CYP3A4 (0.41) | BMP1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL6024770 | 0.75 | BMP1 (0.44) | BMP1MMP12 | |
| SCHEMBL6024907 | 0.73 | HDAC3 (0.39) | BMP1MMP12 | |
| SCHEMBL6025328 | 0.72 | HPGD (0.42) | GAARAB9ABMP1KDM4ELMNA | |
| SCHEMBL6023729 | 0.72 | BMP1 (0.44) | RAB9ABMP1MMP12 | |
| SCHEMBL6024590 | 0.71 | CTSB (0.37) | GAABMP1MMP12SMN1; SMN2 | |
| SCHEMBL6024630 | 0.71 | BMP1 (0.44) | BMP1MMP12 | |
| SCHEMBL6024774 | 0.70 | BMP1 (0.41) | BMP1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363873-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1363873-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070541-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITH KLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |