Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853074 | 0.87 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL6022822 | 0.81 | CA2 (0.47) | MEN1 | |
| SCHEMBL6023415 | 0.80 | KCNH2 (0.42) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL6022154 | 0.79 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1854070 | 0.79 | FFAR1 (0.45) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1855706 | 0.78 | FFAR1 (0.53) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL4324666 | 0.78 | FFAR1 (0.46) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1855191 | 0.78 | FFAR1 (0.46) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1856010 | 0.78 | FFAR1 (0.46) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1854069 | 0.77 | FFAR1 (0.41) | FFAR1FFAR4MMP2MMP12TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | Applied Research Systems ARS Holding N.V. (AN) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005082347-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | APLLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-09-09 | — | — | WO | disclosed |