Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858378 | 0.85 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12ITGB1 | |
| SCHEMBL6023415 | 0.81 | KCNH2 (0.42) | FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL6023918 | 0.79 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12PTPRZ1 | |
| SCHEMBL6023502 | 0.77 | KCNH2 (0.38) | FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL1734789 | 0.76 | MMP2 (0.41) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1855218 | 0.76 | PTGES (0.41) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1851186 | 0.76 | FFAR1 (0.62) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1853670 | 0.75 | PTGES (0.43) | FFAR1FFAR4MMP2MMP12ITGB1 | |
| SCHEMBL4669842 | 0.75 | FFAR1 (0.53) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1851808 | 0.75 | FFAR1 (0.53) | FFAR1FFAR4MMP2MMP12TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | Applied Research Systems ARS Holding N.V. (AN) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005082347-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | APLLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-09-09 | — | — | WO | disclosed |