Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 9/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291472 | 1.00 | TSHR (0.44) | TSHRGGPS1EPHX1ADH1BADH1C | |
| SCHEMBL574091 | 1.00 | TSHR (0.44) | TSHRGGPS1EPHX1ADH1BADH1C | |
| SCHEMBL29291478 | 1.00 | TSHR (0.44) | TSHRGGPS1EPHX1ADH1BADH1C | |
| SCHEMBL28620996 | 1.00 | TSHR (0.44) | TSHRGGPS1EPHX1ADH1BADH1C | |
| SCHEMBL811537 | 1.00 | TSHR (0.44) | TSHRGGPS1EPHX1ADH1BADH1C | |
| SCHEMBL2046476 | 1.00 | TSHR (0.44) | TSHRGGPS1EPHX1ADH1BADH1C | |
| SCHEMBL2573738 | 1.00 | TSHR (0.44) | TSHRGGPS1EPHX1ADH1BADH1C | |
| SCHEMBL12361093 | 1.00 | TSHR (0.44) | TSHRGGPS1EPHX1ADH1BADH1C | |
| SCHEMBL5498660 | 1.00 | TSHR (0.44) | TSHRGGPS1EPHX1ADH1BADH1C | |
| SCHEMBL1068830 | 1.00 | TSHR (0.44) | TSHRGGPS1EPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416118-A | Enzyme inhibitors | SCHERING CORPORATION (US) | 1995-05-16 | — | — | US | claimed |
| EP-0583346-A1 | BICYCLIC AMIDES AS INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL ACYL TRANSFERASE | SCHERING CORPORATION (US) | 1994-02-23 | — | — | EP | claimed |
| EP-0514851-A1 | N-acyl-tetrahydroisoquinolines as inhibitors of acyl-coenzyme a:cholesterol acyl transferase | SCHERING CORPORATION (US) | 1992-11-25 | — | — | EP | claimed |
| WO-1992018462-A1 | BICYCLIC AMIDES AS INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL ACYL TRANSFERASE | SCHERING CORPORATION (US) | 1992-10-29 | — | — | WO | claimed |
| EP-0508425-A1 | Bicyclic amides as inhibitors of acyl-coenzyme a: cholesterol acyl transferase | SCHERING CORPORATION (US) | 1992-10-14 | — | — | EP | claimed |
| US-5124337-A | Treating atherosclerosis | SCHERING CORPORATION (US) | 1992-06-23 | — | — | US | claimed |
| CN-109790284-B | Polyphenol compound and process for producing the same | 三菱化学株式会社 | 2021-09-21 | — | — | CN | disclosed |
| CN-109790284-A | Polyphenol compound and process for producing the same | 三菱化学株式会社 | 2019-05-21 | — | — | CN | disclosed |
| EP-1286651-B1 | USE OF AMINOBENZOIC ACIDS IN COMPOSITIONS WITH PERFUMES | QUEST INT SERV BV (NL) | 2006-08-02 | — | — | EP | disclosed |
| US-20040067870-A1 | Fragrance raw materials aldehydes and pro-fragrances having a tertiary alpha carbon atom | THE PROCTER & GAMBLE COMPANY | 2004-04-08 | — | — | US | disclosed |
| EP-1286651-A1 | IMPROVEMENTS IN OR RELATING TO PERFUMES | QUEST INTERNATIONAL NEDERLAND BV (NL) | 2003-03-05 | — | — | EP | disclosed |
| EP-1171556-A1 | FRAGRANCE RAW MATERIALS ALDEHYDES AND PRO-FRAGRANCES HAVING A TERTIARY ALPHA CARBON ATOM | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2001093823-A1 | IMPROVEMENTS IN OR RELATING TO PERFUMES | QUEST INTERNATIONAL B.V. (NL) | 2001-12-13 | — | — | WO | disclosed |
| US-5789400-A | CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1998-08-04 | — | — | US | disclosed |
| US-5726168-A | Lipophilic benzothiophenes | ELI LILLY AND COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1997013764-A1 | LIPOPHILIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |
| US-5416118-A | Enzyme inhibitors | SCHERING CORPORATION (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0583346-A1 | BICYCLIC AMIDES AS INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL ACYL TRANSFERASE | SCHERING CORPORATION (US) | 1994-02-23 | — | — | EP | disclosed |
| WO-1992018462-A1 | BICYCLIC AMIDES AS INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL ACYL TRANSFERASE | SCHERING CORPORATION (US) | 1992-10-29 | — | — | WO | disclosed |
| EP-0508425-A1 | Bicyclic amides as inhibitors of acyl-coenzyme a: cholesterol acyl transferase | SCHERING CORPORATION (US) | 1992-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067870-A1 | Fragrance raw materials aldehydes and pro-fragrances having a tertiary alpha carbon atom | CUTA, TRPA1, HRH1 | TSHR 4138/4885GGPS1 2132/4885EPHX1 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.