Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | IDE | P14735 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL6023532 | 0.89 | LMNA (0.45) | SIGMAR1IDEKMT2AUBE2NNR3C1 | |
| Fumaric Acid SCHEMBL6023542 | 0.89 | LMNA (0.45) | SIGMAR1IDEKMT2AUBE2NNR3C1 | |
| SCHEMBL6023654 | 0.77 | HTR1B (0.41) | SIGMAR1KMT2AMEN1ADRB2CYP1A2 | |
| Hydrochloric Acid SCHEMBL6023966 | 0.76 | HTR1B (0.40) | SIGMAR1KMT2AMEN1ADRB2CYP1A2 | |
| SCHEMBL27318580 | 0.76 | CYP1A2 (0.46) | SIGMAR1KMT2ANR3C1PGRNR3C2 | |
| SCHEMBL2487482 | 0.75 | HTR2A (0.54) | KMT2ANR3C1MEN1APAF1 | |
| SCHEMBL6024202 | 0.75 | HTR2A (0.54) | KMT2ANR3C1MEN1APAF1 | |
| Hydrochloric Acid SCHEMBL6024099 | 0.74 | HTR2A (0.52) | KMT2ANR3C1MEN1APAF1 | |
| Hydrochloric Acid SCHEMBL2485461 | 0.74 | SIGMAR1 (0.44) | SIGMAR1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6023874 | 0.74 | CYP2A6 (0.44) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957080-B1 | NOVEL ETHYLAMINE DERIVATIVES | FUJIMOTO BROTHERS CO LTD (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-6214859-B1 | PSYCHOLOGICAL DISORDERS; ALZHEIMER'S DISORDERS; PARKINSON'SDISORDERS | FUJIMOTO BROTHERS CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0957080-A1 | NOVEL ETHYLAMINE DERIVATIVES | Fujimoto Brothers Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |