Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024990 | 0.93 | PDE2A (0.38) | PDE2ARAB9APDE4APDE4BPDE4C | |
| SCHEMBL6023491 | 0.83 | PDE2A (0.44) | PDE2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6024368 | 0.83 | PDE2A (0.46) | PDE2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6024717 | 0.83 | PDE2A (0.46) | PDE2ARAB9APDE4APDE4BPDE4C | |
| SCHEMBL6023455 | 0.82 | PDE2A (0.43) | PDE2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6023285 | 0.81 | PDE2A (0.38) | PDE2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6024017 | 0.81 | PDE2A (0.41) | PDE2ARAB9APDE4APDE4BPDE4C | |
| SCHEMBL359546 | 0.79 | PDE2A (0.51) | PDE2ASMN1; SMN2 | |
| SCHEMBL6023286 | 0.79 | PDE2A (0.37) | PDE2ATSHRPDE5A | |
| SCHEMBL6024621 | 0.77 | PDE2A (0.36) | PDE2ANPC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | ALTANA PHARMA AG (DE) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | PDE4B, PDE4A, PDE2A | PDE2A 3/4885PARP1 267/4885RAB9A 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.