Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ABL2 | P42684 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024467 | 1.00 | MAOA (0.41) | MAOAMAOBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6024106 | 0.79 | CYP2A6 (0.47) | MAOAKDM4EALDH1A1ABL1EGFR | |
| SCHEMBL6024107 | 0.79 | CYP2A6 (0.47) | MAOAKDM4EALDH1A1ABL1EGFR | |
| SCHEMBL8629347 | 0.77 | FBP1 (0.64) | MAOAMAOBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8629342 | 0.77 | FBP1 (0.64) | MAOAMAOBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7260095 | 0.76 | FBP1 (0.56) | MAOAMAOBALDH1A1FBP1 | |
| SCHEMBL7260091 | 0.76 | FBP1 (0.56) | MAOAMAOBALDH1A1FBP1 | |
| SCHEMBL6023408 | 0.75 | ABL1 (0.35) | KDM4EALDH1A1ABL1EGFRABL2 | |
| SCHEMBL6023410 | 0.75 | ABL1 (0.35) | KDM4EALDH1A1ABL1EGFRABL2 | |
| SCHEMBL6024491 | 0.75 | CYP2A6 (0.46) | MAOAMAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957080-B1 | NOVEL ETHYLAMINE DERIVATIVES | FUJIMOTO BROTHERS CO LTD (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-6214859-B1 | PSYCHOLOGICAL DISORDERS; ALZHEIMER'S DISORDERS; PARKINSON'SDISORDERS | FUJIMOTO BROTHERS CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0957080-A1 | NOVEL ETHYLAMINE DERIVATIVES | Fujimoto Brothers Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |