Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024491 | 1.00 | CYP2A6 (0.46) | CYP2A6LMNAMAPTRAB9AMAPK1 | |
| SCHEMBL3952660 | 0.85 | CYP2A6 (0.50) | CYP2A6LMNAMAPTRAB9AMAPK1 | |
| SCHEMBL13904618 | 0.85 | CYP2A6 (0.50) | CYP2A6LMNAMAPTRAB9AMAPK1 | |
| SCHEMBL2803711 | 0.79 | CYP2A6 (0.53) | CYP2A6LMNAMAPTRAB9AMAPK1 | |
| SCHEMBL2803709 | 0.79 | CYP2A6 (0.53) | CYP2A6LMNAMAPTRAB9AMAPK1 | |
| SCHEMBL2803708 | 0.79 | CYP2A6 (0.53) | CYP2A6LMNAMAPTRAB9AMAPK1 | |
| SCHEMBL12320812 | 0.76 | CYP2A6 (0.44) | CYP2A6LMNAMAPTRAB9AMAPK1 | |
| SCHEMBL6024464 | 0.75 | MAOA (0.41) | ALDH1A1KDM4EMAOBMAOA | |
| SCHEMBL6024467 | 0.75 | MAOA (0.41) | ALDH1A1KDM4EMAOBMAOA | |
| SCHEMBL6024534 | 0.72 | MAPT (0.51) | CYP2A6MAPTMAPK1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957080-B1 | NOVEL ETHYLAMINE DERIVATIVES | FUJIMOTO BROTHERS CO LTD (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-6214859-B1 | PSYCHOLOGICAL DISORDERS; ALZHEIMER'S DISORDERS; PARKINSON'SDISORDERS | FUJIMOTO BROTHERS CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0957080-A1 | NOVEL ETHYLAMINE DERIVATIVES | Fujimoto Brothers Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |