Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | MAPT | P10636 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | SLC6A5 | Q9Y345 | 7/20 | 0.70 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917331 | 0.97 | ALDH1A1 (0.82) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL3931679 | 0.94 | ALDH1A1 (0.88) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL3923416 | 0.93 | ALDH1A1 (0.86) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL3929006 | 0.88 | SLC6A5 (0.81) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL3919658 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL27859063 | 0.87 | ALDH1A1 (0.75) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL4424938 | 0.86 | MAPT (1.00) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL3931280 | 0.86 | ALDH1A1 (0.83) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL3921674 | 0.84 | SLC6A5 (0.98) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL1689566 | 0.83 | SLC6A5 (1.00) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663232-A1 | 1-(2-AMINO-BENZOYL)-PIPERAZINE DERIVATIVES AS GLYCINE UPTAKE INHIBITORS FOR THE TREATMENT OF PSYCHOSES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005023260-A1 | 1- (2-AMINO-BENZOL) -PIPERAZINE DERIVATIVES AS GLYCINE UPTAKE INHIBITORS FOR THE TREATMENT OF PSYCHOSES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-03-17 | — | — | WO | disclosed |